Category: Research

Studies Enrolling at Lincoln Research — July 2016


Lincoln Research is looking for volunteers for several studies exploring different conditions and treatment options. Here are some of the studies we’re conducting right now. This list changes often, so make sure to like us on Facebook or subscribe to our newsletter for updates.

Migraine Studies

We have two different studies looking for volunteers who suffer from migraine headaches. Information on both is here:

Migraine fixed


Bipolar Disorder

We’re also looking for patients with Bipolar Disorder for a study. Information is here:



We’re looking for subjects with depression (Major Depressive Disorder) to volunteer for a new study. You can find more information on our website or check out depression resources on our blog, here.


For our study on schizophrenia, we’re interested in speaking to people who suffer from schizophrenia, caretakers of patients with schizophrenia, and clinicians who treat patients with schizophrenia. You can find more information on our website or call at (401) 305-5200.

If interested in participating in a study, call (401) 305-5200 or contact us using our web form.

Current Studies at Lincoln Research


Lincoln Research is a clinical research site dedicated to high-quality patient care. We specialize in research of psychiatric conditions such as Major Depressive Disorder (MDD), but have conducted studies in a wide variety of areas. If you’re interested in participating in a study, but none of our current studies interest you, be sure to check back in on our study listings page every couple of months to see what’s new.

Here are the studies we have going right now.


Migraine fixed


Are you or a loved one currently taking Invega Sustenna (paliperidone palmitate) for the treatment of schizophrenia and not having an adequate response?

This study is investigating whether a newly FDA-approved medicine may provide adequate treatment for your symptoms of schizophrenia

To be eligible for this study, you must:

  • Be 18 to 65 years of age
  • Have a diagnosis of schizophrenia
  • Have received at least 3 doses of Invega Sustenna (paliperidone palmitate) prior to the study

Call our office to see if this clinical trial may be appropriate for you!

Genetic Testing for Depression


To stay updated with information about new opportunities at Lincoln Research, like us on Facebook or subscribe to our monthly newsletter.

Is a lack of sexual desire affecting your relationship?

Missing your desire? Call Lincoln Research!

If decreased sexual desire is affecting your connection, it’s time to take the next step to reconnect!

Decreased sexual desire is a real medical condition, known as Hypoactive Sexual Desire Disorder (HSDD). The Reconnect Study is a clinical research study designed to evaluate the safety and effectiveness of a take “as needed” investigational medication for women with decreased sexual desire.

Why Participate?

  • You will receive all study-related medical care at no cost.
  • You will be seen by a study doctor who understands decreased sexual desire.
  • You may be reimbursed for time and travel.

You may qualify if you:

  • Have experienced a decrease in your sexual desire over time;
  • Feel distressed about your decreased sexual desire;
  • Have been in a committed relationship for at least six months;
  • Have not yet gone through menopause.

Contact Lincoln Research to see if you qualify:
(401) 305-5200

Questions to Ask About Clinical Trials

Photo courtesy of: Ambro

Photo courtesy of: Ambro

Generally when looking to join a clinical trial people have many questions they want to ask, but don’t know which questions are the right ones. CISCRP, an organization dedicated to providing the public, patients, and research communities with information about clinical research, has come up with a series of questions that every patient has the right to ask.

The following questions can be directed at any member of the research staff including doctors, nurses, or study coordinators. These questions not only pertain to patients but family members, friends and volunteers.

  1. What is the main purpose of this study?
  2. Does the study involve a placebo or a treatment that is already on the market?
  3. How will the treatment be given to me?
  4. How long is the study going to last and what will I be asked to do as a participant?
  5. What has been learned about the study treatment and are any study results published?
  6. Do I have to pay for any part of the study? Will my insurance cover these costs?
  7. Is there any reimbursement for travel costs or childcare?
  8. Will I be able to see my own doctor?
  9. If the treatment works for me, can I keep using it after the study?
  10. Can anyone find out whether I’m participating in the clinical trial?
  11. Will I receive any follow-up care after the study has ended?
  12. What will happen to my medical care if I stop participating in the study?
  13. Does the physician/investigator have any financial or special interest in the clinical study?
  14. What are the credentials and research experience of the physician and study staff?

If you are considering participating in a clinical trial, take a look at our research studies page for clinical trials we are currently conducting.



Why Participate in a Clinical Trial?


Myths & Facts about Clinical Trials

Photo courtesy of: Naypong

Photo courtesy of: Naypong

Debunking the common myths about clinical trials:

  1. Myth: Volunteers are the guinea pigs of the trial.

Fact: Every trial has a permission for the trial (consent). The volunteers are provided with all the information needed for them to understand the purpose, required activities, possible risks and benefits as well as the purpose of the trial.

  1. Myth: Some of the volunteers are rejected from the process. The process of choosing volunteers is unfair.

Fact: Clinical trials have certain requirements and rules (sex, age, health conditions) that must be met for someone to participate in a trial. Therefore patients who do not match the requirements that the research requires cannot qualify for the trial.

  1. Myth: The trial includes painful and unpleasant parts.

Fact: Each trial has different activities and treatments. The doctors always make sure to fully inform you about any unpleasant parts of the process. Therefore you are very prepared and informed about all the steps of the trial.  Moreover all trials are IRB approved. The IRB checks to see that the benefits and risks are carefully weighed and that the trial is reviewed for unnecessary harm/discomfort before it starts.

  1. Myth: Volunteer is not helped by a clinical trial.

Fact: Taking place in a clinical trial might improve your medical condition. Furthermore, you might also get more tests and run lab work which could most possibly help you to learn more about your condition, as well as receive a drug that would not otherwise be available to you.

  1. Myth: My personal doctor will inform me in case there is a clinical trial that could help me.

Fact: Your doctor may not know about all available clinical trials. The National Institute of Health has an online database that you can search to find appropriate trials: Unfortunately, using that database requires quite a bit of skill (more than many medical practitioners have), so it’s worth making contact with a patient advocacy group. Many of them have tailored services that can help you with your search.

If you are interested in learning more about the facts of clinical trials, speak with us today to learn more!


The Placebo Effect

You may have heard of cases in which a patient who (wrongly) thinks he’s being treated for a condition actually gets better. Medical history is full of extraordinary cases in which patients have recovered from severe conditions through only the power of hope, expectation, and suggestion. But even in ordinary cases, patients and doctors alike are unconsciously affected by their expectations. We call this “the placebo effect.”

For most of history, this has made it hard to determine which treatments were actually helpful. Many traditional remedies have sometimes been effective because they were believed to be effective. Before we had scientific medical research, we could only trust stories and theories. Now that we know how to get at the truth through the scientific method, we still use the placebo effect, but we use it to make our research as precise as possible.


Experiment, Variable, and Control

Just because a medicine really works doesn’t mean you aren’t experiencing a placebo effect. Any perception that you’re getting treatment has the potential to alter the way your mind and body responds to illness.

“Placebo” is a Latin word meaning “I will please.” The idea that we’re taking steps to improve our health is pleasing to us. Eating healthier food will help us feel healthier; taking an aspirin might make it easier to ignore a headache, even before the aspirin kicks in. On the other end, we also want to please others, including our doctors. Many patients who start new treatments will emphasize their improvement to their doctors rather than disappointing them.

This can be a problem for clinical researchers. Researchers only want to test one variable in their experiment—whether a certain medication is better than nothing. But there are many variables that affect your health. The way your doctor treats you, the length of time you spend talking to your doctor, and even the size and color of the pills you take can affect the way you respond to treatment.

To get around this problem, researchers set up a “control” experiment. This is the same as the main experiment, with the only change being the experimental variable. This means that subjects in the control and experimental groups need to experience the same degree of placebo effect.

Typically, both groups are given a drug that they have been informed may or may not be real. This ensures that nobody is lied to, and also decreases the patient’s expectation of recovery, minimizing the placebo effect. The less pronounced the placebo effect, the easier it is to gauge the effectiveness of a treatment. In most placebo-controlled trials, the doctors also don’t know whether a patient is receiving treatment or a placebo. This way, the doctors will treat both groups of patients the same way until the study is finished.

Researchers are constantly trying to find a way to make medical research as precise as possible. If you want to help, call (401) 305-5200 to find out whether you qualify for a Lincoln Research study.


Clinical Research: An Option for Depression Patients

Healthcare is the science of knowing how the human body and brain work. This science has some a long way in recent years, but there’s still a lot that we don’t know. Depression and mental illness are one area that we’re just beginning to understand.

At one time, depression was thought of as a disease of the soul or spirit, separate from the body. But we now know that depression is a disease that affects the brain in the same way that other diseases affect the heart, lungs, or liver. Depression is a medical condition, and clinical research – the scientific side of medicine – helps us understand how depression works and how it might be treated.


Clinical Research and the Scientific Method

Humans use the scientific method to determine what’s true and what’s false. The scientific method starts with a hypothesis, or idea, that may or may not be true. Then scientists perform experiments to test their idea. These experiments are repeated over and over under different conditions. If the hypothesis can predict the results of the experiments most of the time, it might be true.

When a new drug or treatment is designed, we have to perform different experiments to find out different things about the drug. We need to know whether the treatment is safe, whether it’s effective, whether it’s better than worse than the treatments we already have, and what other effects it might have. This takes a long time to do, and we need a lot of patients to volunteer to help with these experiments.


How To Get Involved

If you’ve failed to respond to conventional depression treatments, you should think about asking your doctor if there are any nearby clinical trials you can join. Here’s what you should know:

–By volunteering, you’re helping contribute to medical science.

–Most clinical trials involve treatments that have already been judged safe for use on humans. Still, doctors will be watching closely for any possible risks to your health.

–You will be paid for time and travel and receive free care and a treatment that may or not help.

–You have the right to understand what the possible effects of your treatment will be; the right to refuse treatment and leave the trial at any time; and right to keep your medical information private. Every part of a trial is voluntary.


If you’re interested in volunteering for a trial, seek more information at or call (401) 305-5200 for a confidential interview to see if our study is right for you.


Powered by WordPress & Theme by Anders Norén